Amplicon Sequencing-Based Noninvasive Fetal Genotyping for RHD-Positive D Antigen-Negative Alleles

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Noninvasive fetal RHD genotyping using cell-free fetal DNA incorporating fetal RASSF1A marker in RhD-negative pregnant women in Korea

risk of HDFN, which can cause fetal anemia, hydrops, and intrauterine fetal death. Babies born with HDFN are at significant risk of neonatal morbidity and mortality [1,2]. Prenatal detection of the fetal RhD status in a pregnant woman with RhD-negative provides useful information for predicting the risk of HDFN and Noninvasive fetal RHD genotyping using cell-free fetal DNA incorporating fetal R...

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Fetal RHD Genotyping Using Maternal Plasma

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Objective Maternal-fetal RhD antigen incompatibility causes approximately 50% of clinically significant alloimmunization cases. The routine use of prophylactic anti-D immunoglobulin has dramatically reduced hemolytic disease of the fetus and newborn. Recently, fetal RHD genotyping in RhD negative pregnant women has been suggested for appropriate use of anti-D immunoglobulin antenatal prophylaxi...

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Fetal RHD Genotyping Using Maternal Plasma

PLEASE NOTE: Contracts exclude from coverage, among other things, services or procedures that are considered investigational or cosmetic. Providers may bill members for services or procedures that are considered investigational or cosmetic. Providers are encouraged to inform members before rendering such services that the members are likely to be financially responsible for the cost of these se...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2019

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2019.307074